![]() ![]() The nature of the proteins translated by the other two mRNAs are still putative. ![]() A protein translated from the 3.0 kb mRNA is considered to be the major capsid protein as well as replicase. Three mRNAs are expressed by TTV, 3.0 and 1.2 and 1.0 kb species. The non-coding region surrounding a short 113 nt GC-rich stretch and occupying approximately one-third of the genome is considered to contain the putative replication origin. However, within a year after birth, the prevalence reaches the same level for children born to both TTV-positive and TTV-negative mothers even without breast-feeding. TTV can be transmitted by mother-to-child infection. Furthermore, TTV sequences have been detected in chickens, pigs, cows and sheep. TTVs are prevalent in non-human primates and human TTV can cross-infect chimpanzees. Currently the working group is proposing the full name for TTV as TorqueTenoVirus and the TTV-like mini virus as TorqueTenoMiniVirus (TTMV) in a new genus Anellovirus (ring). The genome structure of TTV is more related to chicken anaemia virus in the genus Gyrovirus, however, the sequence similarity is minimal except for a short stretch at 3816-3851 of TA278. TTV is distinct from ambisense viruses in the genus Circovirus, since the former genome is negative stranded. TTV was considered to be a member of Circoviridae, but others suggested it conformed to a new family. ![]() TTV was the first human virus with a single stranded circular DNA genome. Reborn is back again and I got two collabs this time A Yugioh Master Duel collab with merrin11 with something special that day tonight Then, on Saturday I will be collabing with EverTruaTTV for some Monopoly Plus. This review tries to summarise the current status of TTV on aspects other than the taxonomic diversity of TTV. Due to the lack of suitable cell systems to support the growth of TTV, the biology of TTV is still obscure. However, the real impact of TTV on liver diseases remains uncertain to date. TT virus (TTV) was found in 1997 from a hepatitis patient without virus markers. ![]()
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